Abcde Rule Abcde Rule helps identify early signs of melanoma by checking Asymmetry, Border, Colour, Diameter, and Evolving changes in moles or skin spots. Regular skin checks using the ABCDE Rule can support early melanoma detection and improve treatment outcomes. https://gpnorthbourne.com.au/the-abcde-rule-how-to-spot-early-signs-of-melanoma/