Tretinoin Cream belongs to the class of medications called retinoids. Tretinoin comes as a lotion (Altreno), cream (Avita, Refissa, Renova, Retin-A), and gel (Atralin, Avita, Retin-A). It’s also used as an ingredient in combination products, such as Solage, Tri-Luma, Veltin, and Ziana.