What Makes Handmade Jewelry Unique? Handmade jewelry is not something new – it is the jewelry that has been sought after by kings and queens in older times, and in today's times, it has been a closet staple – for many decades. Whether you got your handmade jewelry designed by a jeweler which is one-of-a-kind, or you picked up a beautiful handcrafted piece of jewelry on your last vacation, you must have been having many pieces of handmade jewelry. One thing you can say by looking at the pieces of handmade jewelry in your collection, or any handmade jewelry piece you find in stores is, that handmade jewelry is very different and unique.