Understanding the science behind MDMA can help demystify its powerful effects. At the neurological level, MDMA increases the release of several neurotransmitters, including serotonin, dopamine, and norepinephrine. The surge in serotonin is particularly responsible for the mood-lifting effects of the drug. Additionally, MDMA increases the release of hormones like oxytocin and vasopressin, which can heighten feelings of bonding and love.