Pharmacies, hospitals, health departments, doctor’s offices, and self-injectors are all home to sharps and sharps waste. The Centers for Disease Control and Prevention(CDC) reports that sharps injuries are primarily associated with occupational transmission of hepatitis B virus (HBV), hepatitis C virus (HCV), and human immunodeficiency virus (HIV), but they have been implicated in the transmission of more than 20 other pathogens. Can all sharps waste risks be eliminated? No, but proper management in a safe protocol can reduce the risk of sharps injuries through awareness, safe disposal, and state and federal disposal laws to minimize exposure.