4 Signs You are Dealing with Hormonal Acne - Safe Health PC - Ah! Hormonal acne – these painful, pesky, and unpleasant pimples appear at the worst time imaginable. How can you know if you are dealing with hormonal acne versus ordinary acne? Dermatologists use some important characteristics to identify if a pimple is hormonal. Read on to find out how to spot hormonal breakouts.